Studies

The iCARUS Research Portfolio

CURRENT STUDIES

START is a randomized controlled trial testing an mHealth app to optimize HIV treatment as prevention in sexual minority men living with HIV who use stimulants.

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PARTI is a randomized controlled trial testing a positive affect intervention to increase pre-exposure prophylaxis (PrEP) adherence among sexual minority men who use stimulants.

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TRIDENT is a randomized controlled trial examining whether and how depression treatment modifies the gut-brain axis in people with HIV.

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AMETHST is a national cohort of HIV-negative sexual minority men examining whether methamphetamine use alters rectal immune function. It is a randomized controlled trial aimed at increasing the use of pre-exposure prophylaxis.

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ARCHES is a national cohort study to identify the multi-level determinants that modify the associations of stimulant use with viral suppression and inflammation among sexual minority men with HIV.

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PrEP-to-Bay is a pilot randomized controlled trial testing a motivational interviewing intervention to increase PrEP adherence in young sexual minority men with syndemic comorbidities.

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MyTPill uses a counterbalanced design to determine the differential validity of two electronic adherence monitoring strategies (i.e. WisePill vs digital pills) in people with HIV who use opioids or stimulants.

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TITAN is a randomized controlled trial testing novel, trauma-informed care approaches for Cambodian people with Post-Traumatic Stress Disorder (PTSD).

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ARES is a 6-month, prospective cohort study assessing whether the use of methamphetamine triggers activation of the viral reservoir and may correlate with an increase in HIV clinical disease markers.

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PAST STUDIES

The CRUSH study aimed to understand how COVID, HIV, and methamphetamine use impact sexual minority men.

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PRISM 2.0 was a pilot sequential multiple assignment randomized controlled trial testing motivational enhancement interventions to increase PrEP use in sexual minority men who use stimulants.

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PRISM 1.0 was a biobehavioral study conducted in the STI clinic setting to examine correlates of rectal immune function and the rectal microbiome.

ARTEMIS was a randomized controlled trial that demonstrated a positive affect intervention delivered during CM for stimulant abstinence achieved durable viral suppression in sexual minority men with HIV who use methamphetamine.

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